Literature reviewMonnet et al(1) published a review article on the assessment of volume responsiveness in mechanically ventilated patients using cardiac and pulmonary interactions. He explained that mechanical ventilation produces cyclical changes in left ventricular stroke volume due to inspiration-expiratory-induced changes in LV preload. It denotes a dependence on the preload of the left ventricle indirectly from the right ventricle. It also describes various limitations of respiratory variations in the SV for predicting fluid responsiveness. Guidet et al (2) conducted a study in patients with sepsis to find the hemodynamic efficacy and safety between 6% HES 130/0.4 and 0.9% NaCl. He found that the volume requirement was less with HES than with NaCl in the initial phase of fluid resuscitation and the time to achieve hemodynamic stability was also less with HES. There was no difference in AKIN and RIFLE criteria between the two groups. There was also no difference in mortality up to 90 days after resuscitation. Christoph K Hofer et (3) al performed a study to determine which system had the best prediction of fluid responsiveness between FloTrac/Vigileo and the PiCCO plus system, using stroke volume change (SVV) as a predictor of fluid responsiveness. fluid reactivity. The study was performed in patients undergoing elective cardiac surgery. He used a method to induce a change in volume by changing body position from 30° head up to 30° head down. SVV was determined using a Flotrac radial sensor and a PiCCO plus femoral catheter. The decrease in SVV found using Flotrac and PiCCO plus was significant and the correlation between the two SVVs was also significant. He also found that SVV measured using FloTrac had a lower prediction threshold than others.Jan Be...... middle of paper ......ilé. By subcostal approach, the diameter of the IVC was measured at the end of inspiration (D max) and at the end of expiration (D min) using echocardiography and the index of distensibility was calculated (dIVC = Dmax-Dmin/Dmin). Cardiac index (CI) measured by Doppler technique in the pulmonary arterial trunk. Patients with a 15% increase in CI after a volume infusion of 7 ml/kg of plasma expanders were called responders. A strong relationship (r = 0.9) was observed between dIVC at baseline and increasing CI following blood volume expansion. Stawiki SP (11) et al performed a study to compare USG-guided assessment of inferior vena cava collapsibility index (IVC-CI) and central venous pressure. He found an inverse relationship between CVP and IVC-CI. An IVC-CI less than 25% is consistent with euvolemia or hypervolemia, while an IVC-CI greater than 75% suggests intravascular volume depletion...