blog




  • Essay / Cancer cases during pregnancy - 1183

    In this series of patients, there were four cases of nasopharyngeal carcinoma, four cases of major or minor salivary glands, and three carcinomas of the tongue. Diagnosis of head and neck cancer during pregnancy impacted delivery gestation, with the majority delivering preterm to allow for subsequent therapeutic intervention. A patient had a pregnancy termination to undergo treatment. However, all infants recovered well and there were no maternal deaths (to be confirmed). Diagnosis and treatment of cancer before pregnancy does not appear to cause harmful consequences. Head and neck cancer includes a range of cancers that originate in the head and neck. According to Parkin et al., it is the fifth most common cancer worldwide [Parkin, 2005 #5], but it is rare in young women and very rare during pregnancy. Counseling pregnant patients with head and neck cancer can be challenging and prognosis and survival depend on it. on the type, stage and grade of the tumor. One thing is certain: optimal care is provided within the framework of a multidisciplinary approach. Radiological studies, including CT and MRI, play a vital role in establishing the extent of local invasion, determining whether lymph nodes are involved, and helping to stage the disease by detecting metastases. The lungs, liver, and bones are the most common sites of metastatic spread. The maximum recommended radiation doses during pregnancy are 50 mGy [Stovall, 1995 #6]. A CT has a _________ dose that is well below the recommended maximum. MRI is a preferable mode of assessment and even when contrast material has been used, it has not been associated with any teratogenic effects. CT scans may be more widely available and diagnosis of a suspected case should not be delayed because...... middle of article...... major salivary gland cancers published by Hocwald et al in Laryngoscope , positive prognostic factors included female sex, younger age and absence of perineural invasion, absence of facial nerve involvement and negative lymph nodes. ConclusionThe management of head and neck cancers is quite variable, highlighting the importance of multidisciplinary input. Symptoms may be nonspecific but investigations should not be delayed, if indicated. Ideally, although management during pregnancy should be consistent with standard practice in the nonpregnant population, this is not always feasible. Further studies are needed to help determine whether the benefits of radiotherapy during pregnancy in terms of reducing tumor recurrence and death can be weighed against the risks to the fetus. The role of concurrent chemoradiotherapy requires further evaluation in head and neck cancer during pregnancy.