Principalism is antagonistic toward a person's faith and religious beliefs, especially in the area of ​​bioethics. The four main components include autonomy, non-maleficence, beneficence, and justice. These are important questions to consider when meeting patient needs, especially in healthcare. More often than not, there are dilemmas that patients and caregivers must face in anticipation of a better outcome. Ultimately, the well-being of the patient comes first. The family involved in this situation are Mike, Joanne and their identical twins Samuel and James. Their situation forces them to make difficult decisions for one of their sons. James had developed a complication due to kidney failure. Furthermore, non-maleficence, which does no harm, saves their son's life without harming or harming Samuel, the healthy twin. In this case, beneficence consists of offering the best option for assessing risk. In this case, James is on dialysis until he can get the transplant that will save his life. Finally, justice gives James a good chance of survival. One of these will be the main determining factor in deciding how they move forward. However, from a Christian perspective, “sickness, suffering, and infirmity were caused by disobedience to God by interrupting God's peace on earth” (Grand Canyon University, 2015). In this particular case, the parents made the decision to seek God as a solution to their problem, based on their faith and experience. It should be noted that Christians view God as the creator and ruler of creation. As a result, he is relied upon for healing and deliverance. Through God's word, faith, and the testimony of others, it helps strengthen their decision to trust God with such a delicate person. James is not old enough to make a decision or give consent to a medical procedure. When it comes to bioethics, the doctor considers the best interest of the patient in doing no harm (non-malice) as well as beneficence, which results in the best treatment option for the child. The doctor will analyze this from the point of view of knowledge and science rather than faith. In addition, the parent has rights and has received the information; they will therefore exercise their autonomy, whether or not they consent to one or the other procedure or to other