Ethical judgment does not constitute a definitive restriction on the method and production of knowledge in the field of art, but it relatively limits the production of knowledge in the fields of science natural. Since ethical judgment constitutes an authority in the conception and minds of the majority of people, people tend to follow ethical standards and have more difficulty developing their knowledge. Moreover, reason is one of the modes of knowledge and moral principle is a crucial factor that shapes the pursuit of knowledge. Extreme cases in the natural sciences and in certain areas of knowledge violate reason which undermines moral obligation. There are many examples that demonstrate that extreme cases in science, such as scientific experiments involving the death of human beings, are controversial to the public and society at large. Moral good or correctness and ethical judgment potentially prevent people from accessing advanced knowledge and limit the process and method of knowledge due to public opinion and moral dilemmas. However, some artists receive great attention and express their concepts more effectively by questioning ethical judgment in artworks, which reveals that ethical judgment and moral principle expand the methods available in knowledge production in the field of art. field of knowledge, the human brain sampling experiment is an ideal experiment for hormone research and a very representative example of the assertion that ethical judgments relatively restrict the methods available in the production of knowledge in natural sciences. If the experiment is successful, it will help scientists better understand medical and scientific science...... middle of article ...... Cited1. History of medicine: subject to science: human experimentation in America before World War II, Annals of Internal Medicine, American College of Physicians, July 15, 1995 vol. 123 no. 2 1592. Presidential Commission for the Study of Ethical Issues in Medicine, Biomedicine, and Behavioral Research, "Defining Death: Medical, Legal, and Ethical Issues in Determining Death," July 1981.3. Vaughan, R.M. (2007-04-14). "Still breaking boundaries after all these years; the monstrous and the mundane collide in a massive investigation into Carolee Schneemann's taboo-breaking art". The Globe and Mail. p. R18.4. Cézanne, She was a great painter cited in Semmel, Joan; April Kingsley. "Sexual Imagery in Women's Art". Women's Art Journal 1 (1): p. 6.JSTOR 1358010.5. Newman, Amy (02/03/2002). “An innovator who was the hero of her own art.” New York Times.