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Essay / Klebsiella Pneumoniae Klebsiella Pneumoniae is a Gram-negative, encapsulated, lactose-fermenting, nonmotile, facultative anaerobic, urease-positive, indole-negative, rod-shaped bacterium that belongs to the family of Enterobacteriaceae (Tufts University, n.d.). Klebsiella is usually found in the nose or mouth, in the gastrointestinal tract (CDC, 2012). Klebsiella pneumonia was first discovered in 1882 as a pathogen causing pneumonia (). Klebsiella can cause various types of health-related infections in the blood, wounds, as well as surgical site infections (CDC, 2012). A common place to become infected with Klebsiella is in the hospital setting, while being treated for other illnesses. Patients infected this way are usually on a ventilator or intravenous catheter (CDC, 2012). Klebsiella owes its name to Edwin Klebs, a German microbiologist (Obiamiwe, 2013).Etiological agent (causative agent)In patients infected with K. pneumonia, inflammatory mechanisms can cause tissue damage linked to the release of "alarm proteins » (Achouiti, 2012). These alarm proteins are known as Damage Associated Molecular Patterns (DAMPs) and are observed in neutrophils where they potentially affect up to 45 percent of the cytoplasmic protein (Achouiti, 2012). This is harmful because it inhibits the body's ability to fight infection, as neutrophils are the body's natural immune defense. Taxonomic classification The domain of Klebsiella is bacteria, it is part of the phylum Proteobacteria, class Gammaproteobacteria, the order Enterobacteriaceae, the family is Enterobacteriaceae. , the genus is Klebsiella, and finally the species is Klebsiella pneumonia.Mode of transmissionFor a person to be infected with Klebsiella...... middle of paper ......proven by the FDA.ConclusionKlebsiella pneumonia includes a majority of hospital urinary tract infections, soft tissue infections and pneumonia (Podschun and Ullmann, 1998). Occurring primarily in alcoholics and known as a cause of hospital-acquired bacterial pneumonia, Klebsiella is most likely associated with hospitalization, as treatment is vital for survival. A number of factors are still being studied to ensure a vaccine and treatment options have favorable outcomes, as there are currently not many options as this disease is antibiotic resistant to many drugs, which makes it difficult to treat. . However, many healthcare facilities need to focus on sterilization, degermination and ensuring good hygiene to reduce the risk of contamination and the spread of bacteria...
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